Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

Search Within Results

5,911 – 5,925 of 6,657 results

5,911

Medchemexpress LLC Ravidasvir hydrochloride | 1303533-81-4 | 99.9% | 835.82 g/mol | C42H52Cl2N8O6 | 10MG

Ravidasvir hydrochloride is a research-grade small-molecule inhibitor of the hepatitis C virus NS5A protein, supplied as the hydrochloride salt for laboratory studies. It exhibits potent, pan-genotypic antiviral activity and is provided with high purity and supporting documentation for use in biochemical and cellular assays.

Pan-genotypic NS5A inhibitor with potent antiviral activity.
High purity (99.9%) suitable for research applications.
Supplied as a hydrochloride salt for improved solubility handling.
Recommended storage conditions provided to preserve stability.
Includes product datasheet and safety data sheet for lab use.

Pricing & Availability

5,912

Medchemexpress LLC CZC-54252 hydrochloride | 1784253-05-9 | 98.4% | 5 MG

CZC-54252 hydrochloride is a potent and selective LRRK2 inhibitor with IC50 values of 1.28 nM for wild-type LRRK2 and 1.85 nM for G2019S LRRK2. This compound can attenuate G2019S LRRK2-induced human neuronal injury with an EC50 of approximately 1 nM, exhibiting neuroprotective activity.

Potent and selective LRRK2 inhibitor
Attenuates G2019S LRRK2-induced human neuronal injury
Exhibits neuroprotective activity
Molecular weight: 541.45
Chemical formula: C22H26Cl2N6O4S
Appearance: Solid
Color: Light yellow to orange
Recommended storage: 4°C, sealed, away from moisture

Pricing & Availability

5,913

Medchemexpress LLC Tiagabine (hydrochloride) | 145821-59-6 | MFCD00892911 | ≥98% | 1 ML

Tiagabine (hydrochloride) is an anticonvulsant agent and a selective inhibitor of the GAT-1 GABA transporter. It potently and selectively inhibits GABA reuptake and demonstrates neuroprotective properties.

Selective inhibitor of GAT-1 GABA transporter
Potently and selectively inhibits GABA reuptake
Exhibits neuroprotective properties
Protects neurons against mutant huntingtin-induced toxicity
Increases viability of SH-SY5Y cells
Inhibits GABA uptake in mouse GAT1 expressed in HEK293 cells

Pricing & Availability

5,914

Medchemexpress LLC Clemizole hydrochloride | 1163-36-6 | 99.7% | 362.30 | 25 MG

Clemizole hydrochloride is an H1 histamine receptor antagonist that has been shown to inhibit HCV replication. It is also an inhibitor of the TRPC5 channel. It effectively blocks TRPC5 currents and Ca2+ entry in the low micromolar range.

IC50 for RNA binding by NS4B is 24 nM.
EC50 for viral replication is 8 μM.
Inhibits HCV RNA replication in cell culture by suppressing NS4B's RNA binding, with minimal toxicity to the host cell.
Effectively blocks TRPC5 currents and Ca2+ entry in the low micromolar range (IC50=1.0-1.3 μM).
Exhibits selectivity for TRPC5 over TRPC4β, TRPC3, and TRPC6.

Pricing & Availability

5,915

Medchemexpress LLC Nimustine hydrochloride (ACNU) | 55661-38-6 | 98.2% | 309.15 | 1 ML

Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine. It functions as an alkylating agent by inducing DNA double-strand breaks (DSBs) and inter-strand crosslinks (ICLs), which activates the DNA damage response (DDR) signaling pathway. It also activates the p38 MAPK/JNK signaling pathway and demonstrates antitumor activity.

Induces DNA double-strand breaks and inter-strand crosslinks.
Activates DNA damage response signaling.
Activates p38 MAPK/JNK signaling.
Demonstrates antitumor activity.
Exhibits cytotoxicity against human U87MG cells.
Induces apoptosis in LN-229 cells.

Pricing & Availability

5,916

Medchemexpress LLC CCG258208 hydrochloride | 98.1% | 488.94 | 1 MG

CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective GRK2 (G protein-coupled receptor kinase 2) inhibitor (IC50=30 nM). It exhibits 230-fold selectivity over GRK5 and more than 2500-fold selectivity over GRK1, PKA, and ROCK1. This compound can be utilized in heart failure research.

Potent and selective GRK2 inhibitor (IC50=30 nM).
Exhibits 230-fold selectivity over GRK5 (IC50=7.09 μM) and more than 2500-fold selectivity over GRK1 (IC50=87.3 μM), PKA, and ROCK1.
Applicable in heart failure research.
Significant improvement in βAR-stimulated contractility in mouse cardiomyocytes at concentrations as low as 0.1 μM.
Superior half-life in vivo with total plasma drug levels exceeding the GRK2 IC50 for seven hours after a single intraperitoneal administration of 10 mg/kg in CD-1 mice.

Pricing & Availability

5,917

Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 250 MG

Flavoxate hydrochloride is the analytical standard of Flavoxate (hydrochloride), intended for research and analytical applications. It is a potent and competitive phosphodiesterase (PDE) inhibitor, an antispasmodic agent, and a muscarinic mAChR antagonist. It exhibits moderate calcium antagonistic activity and a local anesthetic effect. This product can be used for the research of overactive bladder (OAB) and lower urinary tract infections.

Analytical standard for research and analytical applications.
Potent and competitive phosphodiesterase (PDE) inhibitor.
Antispasmodic agent.
Muscarinic mAChR antagonist.
Shows moderate calcium antagonistic activity.
Possesses local anesthetic effect.
Applicable for research on overactive bladder (OAB) and lower urinary tract infections.
Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.

Pricing & Availability

5,918

Medchemexpress LLC Ladostigil hydrochlo 5mg | 209394-18-3 | 5MG

Ladostigil (TV-3326) hydrochloride is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) with IC50s of 37 1 and 31 8 M for MAO-B and AChE respectively Ladostigil hydrochloride exhibits neuroprotective antioxidant and anti-inflammatory activities Ladostigil can be used for the research of depression and Alzheimer s disease[1 [2 Ladostigil (hydrochloride) is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups

Pricing & Availability

5,919

Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 500 MG

SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound can be used for type 2 diabetes research.

Inhibits human TXNIP promoter activity and reduces TXNIP mRNA and protein levels in INS-1 cells.
Lowers glucagon secretion in TC1-6 cells and decreases glucagon secretion and action in vivo.
Reduces glucagon-induced glucose output from primary hepatocytes and blocks hepatic glucose output in vivo.
Reverses obesity- and Streptozotocin (STZ)-induced diabetes and hepatic steatosis in mice.
Orally bioavailable.
Well-tolerated in male C57BL/6J mice.

Pricing & Availability

5,920

Medchemexpress LLC Gefitinib hydrochloride | 184475-55-6 | 99.8% | 500 MG

Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective, and orally active inhibitor of EGFR tyrosine kinase, with an IC50 of 33 nM. It specifically inhibits EGF-stimulated tumor cell growth with an IC50 of 54 nM and blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Additionally, Gefitinib hydrochloride has been shown to induce autophagy and possesses antitumour activity.

Potent, selective, and orally active EGFR tyrosine kinase inhibitor.
Inhibits EGF-stimulated tumor cell growth.
Blocks EGF-stimulated EGFR autophosphorylation in tumor cells.
Induces autophagy.
Demonstrates antitumour activity.

Pricing & Availability

5,921

Medchemexpress LLC Olprinone hydrochloride | 119615-63-3 | 99.9% | C14H11ClN4O | 50 MG

Olprinone Hydrochloride is a potent phosphodiesterase (PDE) 3 inhibitor, showing IC50s of 0.35 μM for PDE3. It is utilized in research for heart failure due to its positive inotropic and vasodilative effects, and also demonstrates anti-inflammatory activity.

Potent PDE3 inhibitor
Used in research for heart failure
Exhibits positive inotropic and vasodilative effects
Demonstrates anti-inflammatory activity
Modulates inflammation associated with myocardial ischemia-reperfusion injury
Reduces pro-inflammatory cytokines such as TNF-α and IL-1β
Decreases expression of adhesion molecules like ICAM-1 and P-Selectin
Inhibits apoptosis related to myocardial injury

Pricing & Availability

5,922

Medchemexpress LLC Dyclonine hydrochloride | 536-43-6 | 99.3% | 1 ML

Dyclonine hydrochloride, also known as Dyclocaine hydrochloride, is an orally effective covalent inhibitor of Aldehyde Dehydrogenase (ALDH) that can cross the blood-brain barrier. It demonstrates sensitizing activities for targeted cancer cells and exhibits antibacterial properties. Additionally, Dyclonine hydrochloride functions as a local anesthetic, capable of suppressing or relieving pain by blocking the transmission of nerve impulses and inhibiting the sensation of touch and pain.

Orally effective ALDH covalent inhibitor
Crosses the blood-brain barrier
IC50 of 35 μM for ALDH2 and 76 μM for ALDH3A1
Sensitizes targeted cancer cells
Possesses antibacterial activity
Acts as a local anesthetic to suppress and relieve pain
Blocks the transmission of nerve impulses
Inhibits the sensation of touch and pain

Pricing & Availability

5,923

Medchemexpress LLC Midodrine hydrochloride | 43218-56-0 | 99.9% | 10 MG

Midodrine hydrochloride is a selective and orally active adrenergic α1-receptor agonist. It strengthens vascular contraction and is utilized in research concerning cardiovascular diseases, such as orthostatic hypotension.

Selective and orally active adrenergic α1-receptor agonist
Strengthens vascular contraction
Utilized in research for cardiovascular diseases like orthostatic hypotension
Increases p-AMPK and PPARδ expression
Increases Ca2+ in C2C12, HL1 and HepG2 cells
Increases maximal mitochondrial oxidative phosphorylation and ATP content in C2C12 cells
Reduces cellular lipid content in 3T3-L1 cells
Reduces platelet-activating factor-induced death in mice
Shows anti-hypotensive effects in orthostatic hypotension rat models
Relieves hypertension in spontaneously hypertensive rat models

Pricing & Availability

5,924

Medchemexpress LLC Alectinib (Hydrochloride) | 1256589-74-8 | 99.9% | 100 MG

Alectinib Hydrochloride is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner). It effectively inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively, and demonstrates effective central nervous system (CNS) penetration.

Potent, selective, and orally available ALK inhibitor
Effective central nervous system (CNS) penetration
Molecular formula: C30H35ClN4O2
Molecular weight: 519.08
Appearance: White to off-white solid
Recommended storage at 4°C, sealed and away from moisture

Pricing & Availability

5,925

Medchemexpress LLC SB-277011 (hydrochloride) | 215804-67-4 | 99.6% | 475.02 | 25 MG

SB-277011 hydrochloride is a potent, selective, orally bioavailable, and brain-penetrant dopamine D3 receptor (D3R) antagonist. It demonstrates 80- to 100-fold selectivity over other dopamine receptors.

Ki values of 10.7 nM and 11.2 nM at rodent and human D3R, respectively.
Selectivity over D2, 5-HT1B, and 5-HT1D receptors.
Oral bioavailability of 43% and a half-life of 2.0 h in rats.
High brain-penetrant (brain:blood ratio of 3.6:1).
Reverses quinelorane effects in the nucleus accumbens at 3 mg/kg (p.o.) in rats.
Reduces intravenous cocaine self-administration in rats (12.5-25 mg/kg, i.p.).
Inhibits basal and cocaine-enhanced locomotion in rats at 50 mg/kg.

Pricing & Availability

Alcohols and polyols

Filtered Search Results

Narrow Results

Medchemexpress LLC Ravidasvir hydrochloride | 1303533-81-4 | 99.9% | 835.82 g/mol | C42H52Cl2N8O6 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CZC-54252 hydrochloride | 1784253-05-9 | 98.4% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tiagabine (hydrochloride) | 145821-59-6 | MFCD00892911 | ≥98% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Clemizole hydrochloride | 1163-36-6 | 99.7% | 362.30 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nimustine hydrochloride (ACNU) | 55661-38-6 | 98.2% | 309.15 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CCG258208 hydrochloride | 98.1% | 488.94 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ladostigil hydrochlo 5mg | 209394-18-3 | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Gefitinib hydrochloride | 184475-55-6 | 99.8% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Olprinone hydrochloride | 119615-63-3 | 99.9% | C14H11ClN4O | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dyclonine hydrochloride | 536-43-6 | 99.3% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Midodrine hydrochloride | 43218-56-0 | 99.9% | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alectinib (Hydrochloride) | 1256589-74-8 | 99.9% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SB-277011 (hydrochloride) | 215804-67-4 | 99.6% | 475.02 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More